TITLE Basic Potassium current
COMMENT
from "Gamma Oscillation by Synaptic Inhibition in a Hippocampal Interneuronal Network Model" (Wang and Buzsaki 1996)
Used in Role of a Striatal Slowly Inactivating Potassion Current in Shortterm Facilitation of Corticostriatal Inputs" A computer Simulation Study" (Mahon et al. 2000)
Implemented by Kevin M. Biddell kevin.biddell@gmail.com
7/12/06
NOTE: 1S=1mho Neuron wants the units in mhos not millisiemens, please note the conversion!
Phi =5 and no q10 or temp adjustment according to Bruno Delord 11/13/06
ENDCOMMENT
UNITS {
(mA) = (milliamp)
(mV) = (millivolt)
}
NEURON {
SUFFIX Km
USEION k WRITE ik
RANGE gkmbar, gkm, ninf, an, Bn
}
INDEPENDENT {t FROM 0 TO 1 WITH 1 (ms)}
PARAMETER {
ek = 90 (mV)
gkmbar = 0.006 (mho/cm2) : 6mS
phi = 5 < 0, 1e9 > : according to Bruno delord 11/13/06
Van = 27 :NOT the original value from wang and Buzsaki
Kan = 1
Vbn = 37 :NOT the original value from wang and Buzsaki
Kbn = 80
}
STATE {
n
}
ASSIGNED {
v (mV)
ik (mA/cm2)
celsius (degC)
ninf
an
Bn
gkm
}
BREAKPOINT {
SOLVE states METHOD cnexp
gkm = gkmbar*n^4
ik = gkm*(v  ek)
}
UNITSOFF
INITIAL {
rates(v)
n= ninf
}
DERIVATIVE states { :Computes states variable n
rates(v) : at the current v and dt.
n'=phi*(an*(1n)Bn*n)
}
PROCEDURE rates(v) { :Computes rate and other constants at current v.
:Call once from HOC to initialize inf at resting v.
an = (0.01*(vVan)/Kan/(exp(0.1*(vVan)/Kan)1))
Bn = 0.125*exp((vVbn)/Kbn)
ninf = an/(an+Bn)
}
UNITSON
