In Situ Observation of Reduction Behavior of Hemoglobin Molecules Adsorbed on Glass Surface

Masayoshi MATSUI  Akiko NAKAHARA  Akiko TAKATSU  Kenji KATO  Naoki MATSUDA  

IEICE TRANSACTIONS on Electronics   Vol.E89-C   No.12   pp.1741-1745
Publication Date: 2006/12/01
Online ISSN: 1745-1353
DOI: 10.1093/ietele/e89-c.12.1741
Print ISSN: 0916-8516
Type of Manuscript: Special Section PAPER (Special Section on Towards the Realization of Organic Molecular Electronics)
Category: Evaluation of Organic Materials
slab optical waveguide spectroscopy,  hemoglobin,  adsorption,  reduction,  solid/liquid interface,  

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In situ observation of the adsorption process and reduction behavior of hemoglobin adsorbed on a bare glass surface was studied using slab optical waveguide (SOWG) spectroscopy. The peak position of the absorption band of hemoglobin adsorbed on the glass surface was almost the same as that of hemoglobin in solution. This result agrees with results previously reported by our group. The adsorbed hemoglobin molecules were also reduced by sodium dithionite solution. The adsorbed hemoglobin molecules still maintained their function in this experimental condition.