Improvement of the Time-Domain Response of a Thermodilution Sensor by the Natural Observation System

Jun'ichi HORI  Yoshiaki SAITOH  Tohru KIRYU  

Publication
IEICE TRANSACTIONS on Fundamentals of Electronics, Communications and Computer Sciences   Vol.E77-A   No.5   pp.784-791
Publication Date: 1994/05/25
Online ISSN: 
DOI: 
Print ISSN: 0916-8508
Type of Manuscript: Special Section PAPER (Special Section on Signal Processing and System Theory)
Category: 
Keyword: 
thermodilution,  natural observation system,  ejection fraction,  rise time,  step-response,  real time,  

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Summary: 
When measuring the ejection fraction for the evaluation of the ventricular pumping function by means of the thermodilution technique, the slow response a conventional thermistor has caused it to be considered unsuitable, and fast thermistors have been proposed as an alternative. However, in this paper we propose improving the time-domain response of a conventional thermistor using a signal processing technique composed of a series of first-order high-pass filters which is known as the natural observation system. We considered the rise time of the thermistor in response to a step temperature change to effect correction for the measurement of the ejection fraction. The coefficients of the natural observation system were calculated by minimizing the square error between the step-response signal of the thermistor and the band-limited reference signal. In an experiment using a model ventricle, the thermodilution curve obtained from a conventional thermistor was improved using the proposed technique, thus enabling successful measurement of the ejection fraction of the ventricles.