Design and Analysis of Scalability in Current-Mode Analog-to-Time Converter for an Energy-Efficient and High-Resolution CMOS Biosensor Array

Kei IKEDA  Atsuki KOBAYASHI  Kazuo NAKAZATO  Kiichi NIITSU  

Publication
IEICE TRANSACTIONS on Electronics   Vol.E100-C   No.6   pp.597-601
Publication Date: 2017/06/01
Online ISSN: 1745-1353
Type of Manuscript: BRIEF PAPER
Category: 
Keyword: 
bioimaging,  time-domain,  current-mode,  

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Summary: 
High-resolution bio-imaging is a key component for the advancement of life science. CMOS electronics is one of the promising candidates for emerging high-resolution devices because it offers nano-scale transistors. However, the resolution of the existing CMOS bio-imaging devices is several micrometers, which is insufficient for analyzing small objects such as bacteria and viruses. This paper presents the results of an analysis of the scalability of a current-mode analog-to-time converter (CMATC) to develop a high-resolution CMOS biosensor array. Simulations were performed using 0.6-µm, 0.25-µm, and 0.065-µm CMOS technology nodes. The Simulation results for the power consumption and resolution (cell size) showed that the CMATC has high-scalability and is a promising candidate to enable high-resolution CMOS bio-imaging.